Currently, two major Amtrak lines travel through Iowa: California Zephyr – This iconic route runs from Chicago, Illinois to Emeryville, California, covering some of the most scenic landscapes in America. In Iowa, it stops in Burlington, Mount Pleasant, Ottumwa, Osceola, and Creston. Southwest Chief – Running from Chicago to Los Angeles, this historic route serves only one station in Iowa: Fort Madison. However, it connects passengers to the American Southwest in spectacular fashion. Together, these two routes give Iowans access to both coasts—and everything in between.